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1

Decoys, dikes and lures: polyfunctional landscapes of waterfowl hunting

Journal:

Studies in the History of Gardens & Designed Landscapes

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

2

Anti-thrombotic and haemorrhagic effects of active site-inhibited factor VIIa in rats

F. Ghrib, P. Léger, M. Ezban, A. T. Kristensen, J. P. Cambus, B. Boneu

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 127 KB

english, 2001

3

High-dose factor VIIa increases initial thrombin generation and mediates faster platelet activation in thrombocytopenia-like conditions in a cell-based model system

Marianne Kjalke, Mirella Ezban, Dougald M. Monroe, Maureane Hoffman, Harold R. Roberts, Ulla Hedner

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 234 KB

english, 2001

4

Locations of disulfide bonds and free cysteines in the heavy and light chains of recombinant human factor VIII (antihemophilic factor A)

Brad A. Mcmullen, Kazuo Fujikawa, Earl W. Davie, Ulla Hedner, Mirella Ezban

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 673 KB

english, 1995

5

Artificial contact pathway activation masks the haemostatic potential of rFVIIa and NN1731 in thrombocytopenic whole blood

Ole H. Larsen, Mirella Ezban, Egon Persson, Jørgen Ingerslev, Benny Sørensen

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 124 KB

english, 2010

6

Intravascular inhibition of factor VIIa and the analogue NN1731 by antithrombin

Lars C. Petersen, Ditte M. Karpf, Henrik Agersø, Mette B. Hermit, Hermann Pelzer, Egon Persson, Timothy C. Nichols, Mirella Ezban

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 360 KB

english, 2011

7

Thrombin generation and platelet activation induced by rFVIIa (NovoSeven®) and NN1731 in a reconstituted cell-based model mimicking haemophilia conditions

M. N. ALJAMALI, M. KJALKE, U. HEDNER, M. EZBAN, M. TRANHOLM

Journal:

Year:

2009

Language:

english

File:

PDF, 285 KB

english, 2009

8

Effect of glycoPEGylation on factor VIIa binding and internalization

P. SEN, S. GHOSH, M. EZBAN, U. R. PENDURTHI, L. VIJAYA MOHAN RAO

Journal:

Year:

2010

Language:

english

File:

PDF, 223 KB

english, 2010

9

Animal models of FVIIa gene expression: their role in the future development of haemophilia treatment

A. OBERGFELL, T. NICHOLS, M. EZBAN

Journal:

Year:

2010

Language:

english

File:

PDF, 51 KB

english, 2010

10

Functional characteristics of N8, a new recombinant FVIII

M. L. S. CHRISTIANSEN, K. W. BALLING, E. PERSSON, I. HILDEN, A. BAGGER-SØRENSEN, B. B. SØRENSEN, D. VIUFF, S. SEGEL, N. K. KLAUSEN, M. EZBAN, S. LETHAGEN, T. D. STEENSTRUP, M. KJALKE

Journal:

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

11

Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog

T. KNUDSEN, A. T. KRISTENSEN, T. C. NICHOLS, H. AGERSØ, A. L. JENSEN, M. KJALKE, M. EZBAN, M. TRANHOLM

Journal:

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

12

International comparative field study of N8 evaluating factor VIII assay performance

D. VIUFF, TW. BARROWCLIFFE, T. SAUGSTRUP, M. EZBAN, D. LILLICRAP

Journal:

Year:

2011

Language:

english

File:

PDF, 272 KB

english, 2011

13

Monitoring rFVIIa 90 μg kg−1 dosing in haemophiliacs: comparing laboratory response using various whole blood assays over 6 h

D. F. BROPHY, E. J. MARTIN, J. CHRISTIAN BARRETT, M. E. NOLTE, J. G. KUHN, P. M. GERK, M. E. CARR, H. PELZER, H. AGERSØ, M. EZBAN, U. HEDNER

Journal:

Year:

2011

Language:

english

File:

PDF, 387 KB

english, 2011

14

Pharmacokinetics and pharmacodynamics of a new recombinant FVIII (N8) in haemophilia A mice

T. ELM, D. M. KARPF, K. ØVLISEN, H. PELZER, M. EZBAN, M. KJALKE, M. TRANHOLM

Journal:

Year:

2012

Language:

english

File:

PDF, 302 KB

english, 2012

15

Pharmacokinetics and ex vivo whole blood clot formation of a new recombinant FVIII (N8) in haemophilia A dogs

D. M. KARPF, M. KJALKE, L. THIM, H. AGERSØ, E. P. MERRICKS, N. DEFRIESS, T. C. NICHOLS, M. EZBAN

Journal:

Year:

2011

Language:

english

File:

PDF, 238 KB

english, 2011

16

Activity and regulation of factor VIIa analogs with increased potency at the endothelial cell surface

S. GHOSH, M. EZBAN, E. PERSSON, U. PENDURTHI, U. HEDNER, L. V. M. RAO

Journal:

Journal of Thrombosis and Haemostasis

Year:

2007

Language:

english

File:

PDF, 1012 KB

english, 2007

17

Recombinant human factor VIIa and a factor VIIa-analogue reduces heparin and low molecular weight heparin (LMWH)-induced bleeding in rats

B. LAURITZEN, U. HEDNER, P. B. JOHANSEN, M. TRANHOLM, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

18

Evaluation of the safety and pharmacokinetics of a fast-acting recombinant FVIIa analogue, NN1731, in healthy male subjects

J. MØSS, B. SCHARLING, M. EZBAN, T. MØLLER SØRENSEN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 324 KB

english, 2009

19

rFVIIa and a new enhanced rFVIIa-analogue, NN1731, reduce bleeding in clopidogrel-treated and in thrombocytopenic rats

B. LAURITZEN, M. TRANHOLM, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 273 KB

english, 2009

20

Faster onset of effect and greater efficacy of NN1731 compared with rFVIIa, aPCC and FVIII in tail bleeding in hemophilic mice

H. L. HOLMBERG, B. LAURITZEN, M. TRANHOLM, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

21

Recombinant human factor VIIa (rFVIIa) cleared principally by antithrombin following intravenous administration in hemophilia patients

H. AGERSØ, D. F. BROPHY, H. PELZER, E. J. MARTIN, M. CARR, U. HEDNER, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 199 KB

english, 2011

22

GlycoPEGylated rFVIIa (N7-GP) has a prolonged hemostatic effect in hemophilic mice compared with rFVIIa

H. HOLMBERG, T. ELM, D. KARPF, M. TRANHOLM, S. E. BJØRN, H. STENNICKE, M. EZBAN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 144 KB

english, 2011

23

Platelet binding and activity of a factor VIIa variant with enhanced tissue factor independent activity

M. HOFFMAN, Z. VOLOVYK, E. PERSSON, D. A. GABRIEL, M. EZBAN, D. M. MONROE

Journal:

Journal of Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 377 KB

english, 2011

24

Proteolytic cleavage of recombinant two-chain factor VIII during cell culture production is mediated by protease(s) from lysed cells. The use of pulse labelling directly in production medium

Karen Hansen, Marianne Kjalke, Poul Baad Rasmussen, Leif Kongerslev, Mirella Ezban

Journal:

Year:

1997

Language:

english

File:

PDF, 80 KB

english, 1997

25

DNA-binding proteins in Yoshida ascites tumor fluid

Jens Krøll, Jørgen K. Larsen, Hans Loft, Mirella Ezban, Knut Wallevik, Mogens Faber

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Year:

1976

Language:

english

File:

PDF, 1.20 MB

english, 1976

26

Clearance of rFVIIa and NN1731 after intravenous administration to Beagle dogs

Henrik Agersø, Niels Rode Kristensen, Henrik Østergaard, Ditte Maria Karpf, Mette Brunsgaard Hermit, Hermann Pelzer, Lars Christian Petersen, Mirella Ezban

Journal:

European Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

27

Tissue Factor-dependent Factor VIIa Signaling

Lars C Petersen, Per-Ola Freskgård, Mirella Ezban

Journal:

Trends in Cardiovascular Medicine

Year:

2000

Language:

english

File:

PDF, 509 KB

english, 2000

28

Local application of recombinant active-site inhibited human clotting factor VIIa reduces thrombus weight and improves patency in a rabbit venous thrombosis model

J. Holst, A.T. Kristensen, H.I. Kristensen, M. Ezban, U. Hedner

Journal:

European Journal of Vascular and Endovascular Surgery

Year:

1998

Language:

english

File:

PDF, 646 KB

english, 1998

29

Radioimmunoassay for quantitative measurement of factor VIII-heavy chain

O. Nordfang, M. Ezban, P. Nilsson, J. B. Knudsen

Journal:

British Journal of Haematology

Year:

1988

Language:

english

File:

PDF, 511 KB

english, 1988

30

A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)

A. E. PASTOFT, J. LYKKESFELDT, M. EZBAN, M. TRANHOLM, H. C. WHINNA, B. LAURITZEN

Journal:

Year:

2012

Language:

english

File:

PDF, 177 KB

english, 2012

31

Pharmacokinetics and pharmacodynamics of turoctocog alfa and N8-GP in haemophilia A dogs

H. Agersø, H. R. Stennicke, H. Pelzer, E. N. Olsen, E. P. Merricks, N. A. deFriess, T. C. Nichols, M. Ezban

Journal:

Year:

2012

Language:

english

File:

PDF, 215 KB

english, 2012

32

Amino Acid Residues 721–729 are Required for Full Factor VIII Activity

Marianne Kjalke, Anders Heding, Gert Talbo, Egon Persson, Johannes Thomsen, Mirella Ezban

Journal:

Year:

1995

Language:

english

File:

PDF, 1.69 MB

english, 1995

33

Characterization of Chemically Crosslinked Human Factor VIIIa

E. Persson, M. Ezban

Journal:

Biochemical and Biophysical Research Communications

Year:

1994

File:

PDF, 342 KB

1994

34

Deencryption of Cellular Tissue Factor Is Independent of Its Cytoplasmic Domain

A.S. Wolberg, R.H. Kon, D.M. Monroe, M. Ezban, H.R. Roberts, M. Hoffman

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 51 KB

english, 2000

35

Active-site inactivated FVIIa decreases thrombosis and necrosis in a random skin flap model of acute ischemia

Navid Alizadeh, Brigitte Pittet, Xavier Tenorio, Charles Pyke, Danielle Baetens, Kai-Uwe Schlaudraff, Denys Montandon, Mirella Ezban, Michael S. Pepper

Journal:

Journal of Surgical Research

Year:

2004

Language:

english

File:

PDF, 681 KB

english, 2004

36

Recombinant coagulation factor VIIa – from molecular to clinical aspects of a versatile haemostatic agent

Egon Persson, Gert Bolt, Thomas D. Steenstrup, Mirella Ezban

Journal:

Thrombosis Research

Year:

2010

Language:

english

File:

PDF, 261 KB

english, 2010

37

Recombinant factor VIIa analog NN1731 (V158D/E296V/M298Q-FVIIa) enhances fibrin formation, structure and stability in lipidated hemophilic plasma

Laura D. Gray, Michael A. Hussey, Brittany M. Larson, Kellie R. Machlus, Robert A. Campbell, Gary Koch, Mirella Ezban, Ulla Hedner, Alisa S. Wolberg

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 922 KB

english, 2011

38

Tissue factor in experimental acute lung injury

Karen E Welty-Wolf, Martha S Carraway, Steve Idell, Thomas L Ortel, Mirella Ezban, Claude A Piantadosi

Journal:

Seminars in Hematology

Year:

2001

Language:

english

File:

PDF, 667 KB

english, 2001

39

TISSUE FACTOR PATHWAY INHIBITOR IN COMPLEX WITH LOW DENSITY LIPOPROTEIN ISOLATED FROM HUMAN PLASMA DOES NOT POSSESS ANTICOAGULANT FUNCTION IN TISSUE FACTOR-INDUCED COAGULATION IN VITRO

John-Bjarne Hansen, K.R Huseby, N-E Huseby, M Ezban, A Nordøy

Journal:

Thrombosis Research

Year:

1997

Language:

english

File:

PDF, 2.10 MB

english, 1997

40

Whole blood coagulation in children with thrombocytopenia and the response to platelet replacement, recombinant factor VIIa, and a potent factor VIIa analogue

Ole H. Larsen, Niels Clausen, Egon Persson, Mirella Ezban, Jørgen Ingerslev, Benny Sørensen

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 166 KB

english, 2009

41

Purification and characterisation of the pathological antithrombin III “Aalborg”

P.J. Sørensen, M. Ezban, T.E. Jessen, G. Sas, G. Blasko, M. Jørgensen

Journal:

Thrombosis Research

Year:

1990

Language:

english

File:

PDF, 559 KB

english, 1990

42

Heterogeneity in the tyrosine sulfation Chinese hamster ovary cell produced recombinant FVIII

Mikkelsen, J., Thomsen, J., Ezban, M.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.50 MB

english, 1991

43

Tissue Factor and Factor VIIa as Therapeutic Targets in Disorders of Hemostasis

Hedner, Ulla, Ezban, Mirella

Journal:

Annual Review of Medicine

Year:

2008

Language:

english

File:

PDF, 177 KB

english, 2008

44

Prevention of experimental arterial thrombosis by topical administration of active siteâinactivated factor VIIa

Arnljots, BjÃ¶rn, Ezban, Mirella, Hedner, Ulla

Journal:

Journal of Vascular Surgery

Year:

1997

Language:

english

File:

PDF, 468 KB

english, 1997

45

Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model

Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, J., Lauritzen, B.

Journal:

Year:

2013

Language:

english

File:

PDF, 271 KB

english, 2013

46

CRYOPRECIPITATE PREPARATION

Journal:

Year:

1979

Language:

english

File:

PDF, 116 KB

english, 1979

47

Kinetics of the interaction between the human factor VIIIa subunits: effects of pH, ionic strength, Ca2+ concentration, heparin, and activated protein C-catalyzed proteolysis

Persson, Egon, Ezban, Mirella, Shymko, Ronald M.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.74 MB

english, 1995

48

Turoctocog alfa (NovoEight ® ) - from design to clinical proof of concept

Ezban, Mirella, Vad, Knud, Kjalke, Marianne

Journal:

European Journal of Haematology

Year:

2014

Language:

english

File:

PDF, 613 KB

english, 2014

49

Maurice Baring et la France

Journal:

Year:

1945

File:

PDF, 429 KB

1945

50

Plasma Lipoproteins Enhance Tissue Factor-Independent Factor VII Activation

Kjalke, M., Silveira, A., Hamsten, A., Hedner, U., Ezban, M.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2000

Language:

english

File:

PDF, 580 KB

english, 2000